Chondroid syringoma is a benign, skin appendageal tumor. They are typically found on the eyelids, but may also develop in other parts of the body with sebaceous ducts such as. Chondroid syringoma is a tumor arising from the sweat glands which can be apocrine found throughout the surface of lid or eccrine glands of moll in association with eyelash follicles with a mean age of 50 years 2273 years. We report a case of chondroid syringoma arising from a. Besides, the adnexa of the skin also give rise to appendage tumours like eccrine spiradenoma and chondroid syringoma. Benign chondroid syringoma mixed tumor discussion a chondroid syringoma is a rare mixed tumor of sweatgland origin that has both a benign and malignant form. View the article pdf and any associated supplements and figures for a period of 48 hours. Cutaneous mixed tumor with ductal lumina and myxoid stromasmall ducts lined by cuboidal cells are a common finding. The characteristic feature is a fibrillary chondromyxoid substance in the background, staining purple with giemsa stain and eosinophilic with papanicolaou stain. It is also known as a cutaneous pleomorphic adenoma, benign mixed cutaneous tumour or eccrine mixed tumour as it contains both epithelial and mesenchymal elements. Chondroid syringoma cs of the orbit is an extremely rare benign neoplasm. Pdf chondroid syringoma with extensive ossification. Due to its uncharacteristic presentation, it is rarely diagnosed clinically. For chondroid syringoma, total excision is recommended, 2 while for pleomorphic adenoma, extracapsular dissection or superficial parotidectomy is commonly indicated.
The site of predilection for benign chondroid syringoma is the head and neck region, and it is less likely to involve the foot. Diagnosis is usually revealed by excision followed by histologic examination. Article information, pdf download for chondroid syringoma open epub for. Unlimited viewing of the article pdf and any associated supplements and figures. As far as the latest information is concerned with updated knowledge and visualizing techniques this is the rare case. Rapidly growing chondroid syringoma of the external auditory canal. Outcomesresolutions the prognosis for chondroid syringoma is generally excellent with appropriate treatment, since it is a benign tumor. Chondroid syringoma, also known as mixed tumor of skin, is a benign neoplasm of the sweat glands. Malignant chondroid syringoma with nose and paranasal. Chondroid syringoma is also known as mixed tumour of the skin. Malignant chondroid syringoma is a mixed cutaneous tumor, with epithelial and mesenchymal components, which compromises principally the trunk and extremities. Dermal chondroid syringoma diagnostic histopathology.
Abstract benign chondroid syringomas are benign ad. Sir, chondroid syringoma cs, a tumour of the eccrinesweat gland, was previously called as the mixed tumour of the skin. Chondroid syringoma is a rare, benign skin tumour arising from the sweat glands with an incidence of approximately 0. This skin adenexal tumor is typically located on the head and neck region. Chondroid syringoma is a rare tumor with the potential for malignant transformation and distant metastasis. It is treated surgically and its diagnosis is histological. Chondroid syringoma or mixed tumour of the skin is an uncommon benign sweat gland tumour. Epithelial components derived from folliculosebaceousapocrine germ are evident in apocrine but not in eccrine cs.
Neoplasms with microscopic features that indicate both epithelial and mesenchymal origin have been referred to as. Facial localization of malignant chondroid syringoma. This is seen not only in normal skin but in cutaneous neoplasms as well. The differential diagnosis of chondroid syringoma includes basal cell carcinoma with stromal hyalinization and. Malignant chondroid syringoma mcs is a rare tumor, of the sweat gland. Pdf chondroid syringoma, or pleomorphic adenoma of the skin, is a rare, benign skin adnexal tumor. This benign, mixed epithelial tumor is infrequently seen by the otolaryngologisthead and neck surgeon, and therefore may not be included in the differential diagnosis of a nodular lesion on the skin of the head and neck. Currently, there are no known methods to prevent chondroid syringoma occurrence.
The chondroid syringoma is an extremely rare skin tumor most commonly found in the area of the head and neck region. Chondroid syringoma is a cutaneous mixed tumor of salivaryglandtype usually located in the head and neck region. Benign chondroid syringomas are benign adnexal tumors that occur most commonly in the head and neck region. A mucoid aspirate, abundant chondromyxoid matrix material, and epithelial components were suggested as diagnostic criteria. Giant chondroid syringoma of the axilla david hardisson.
Aug 12, 2018 how can chondroid syringoma be prevented. Chondroid syringoma cs is a benign cutaneous adnexal tumor with epithelial and stromal components. This tumor developed slowly over 8 years causing indolor, no axil, exophtalmos of the left eye. Its rarity, potential for malignancy, and frequent misdiagnosis for other more common tumors can impart unique challenges in diagnosis and management. It includes dermatologic cancer, which can be deadly. Chondroid syringoma, an uncommon, slowgrowing, benign, sweatgland tumor located on the upper right chest wall of a 66yearold woman is presented. In the present literature, reports of the cytologic appearance of cs are scarce as it is rarely encountered by fine needle aspiration fna.
Computed tomography demonstrated an isodense intraorbital tumor with. A well circumscribed but unencapsulated, multilobulated mass centered in deep dermis or subcutaneous fat, with a prominent chondroid or myxoid stroma enveloping benign bland appearing epithelial and myoepithelial cells that form secondary structures. They usually present as firm intradermal or subcutaneous nodules. Histological examination showed cords, nests, and tubuloglandular structures composed of welldifferentiated tumour cells embedded in a hyalinized stroma with abundant chondroid matrix, and the diagnosis of chondroid syringoma was established. A chondroid syringoma is a rare mixed tumor of sweatgland origin that has both a benign and malignant form. Rarely, a chondroid syringoma of many years duration suddenly undergoes malignant changes with widespread metastasis.
The cutaneous lesion has different behaviour in that it rarely recurs even if inadequately excised. We report a case of a 41yearold woman with orbital cs. It is also known as mixed tumor of skin, as it histologically resembles mixed tumor of salivary gland pleomorphic adenoma. Pdf a rare case of malignant chondroid syringoma of scalp. While usually solitary, cases with multiple lesions have been reported. An 81yearold man underwent excisional biopsy of a big cylindric painless mass of the right lower eyelid, which had been present for over 23 years. We use cookies to offer you a better experience, personalize content, tailor advertising, provide social media features, and better understand the use of our services. Collectively, dermatologic cancers are the most common form of cancer. Chondroid syringoma cs, a tumour of the eccrinesweat gland, was previously called as the mixed tumour of the skin. In the present literature, reports of the cytologic appearance of cs are scarce as it. The lesion extended to the peripheral and deep margins.
The term syringoma is derived from the word syrinx, meaning pipe or tube. Chondroid syringoma is a cutaneous sweat gland tumor. Histopathologic and immunohistochemical examination showed a chondroid syringoma, an uncommon benign neoplasm of possible eccrine sweat gland origin, which occurs generally in the head and neck skin. The dermatoscopy does not seem to supply any specific trait to this lesion.
Hirsch and helwig named it chondroid syringoma because of the presence of sweat gland elements in a cartilaginous stroma. Chondroid syringoma is a rare benign skin adnexal tumor of eccrineapocrine origin affecting commonly the head and neck region. To the best of our knowledege, this is the second case reported in the english literature. Giant chondroid syringoma of the breast sereflican. Chondroid syringoma cs is a rare benign adnexal tumor of the skin with a resemblance to pleomorphic adenoma of salivary gland, most commonly involving the head and neck region. Five of the eight cases were apocrine, one of them with follicular and sebaceous differentiation. To further characterize pilosebaceous differentiation and to identify the presence of merkel cells in the areas of follicular differentiation. The chondroid syringoma is usually a smallsized skin tumor, frequently on the head and neck. Chondroid syringomacutaneous mixed tumor low magnificationlow magnification shows a wellcircumscribed tumor composed of epithelial islands with easily identifiable glandularductal structures embedded in a myxoid and hyaline stroma.
Chondroid lesions are extremely common incidental findings on musculoskeletal mri studies, since the femur and humerus are the most common location for chondroid tumors of the appendicular skeleton. It is the cutaneous counterpart of pleomorphic adenoma of the salivary glands. Giant chondroid syringoma of the breast sereflican 2015. We present a case report of chondroid syringoma of the foot in a healthy patient. The wound healed without complications, and no recurrence had been presented during 18month followup. Here we present 10 new cases with their clinicohystological characteristics. Diagnosis of a rapidly growing preauricular nodule. Nonmalignant disease is covered in the nonmalignant skin disease article. Apr, 2018 chondroid syringoma is a rare, benign skin tumour arising from the sweat glands with an incidence of approximately 0. Definitive diagnosis required histopathologic examination, while treatment included wide resection. It was excised and histology showed that this was a chrondriod syringoma which is a benign tumour of the skin appendages. Chondroid definition of chondroid by the free dictionary. Mar 31, 2014 discussion chondroid syringoma also known as mixed tumour of the skin benign adnexal tumour with an unknownaetiopathogenesis.
Department of radiation, oncology, gandhi medical college, bhopal, madhya pradesh, india. All the cases had a myxoid matrix and most also had a chondroid one. They most often arise on the skin of the head and neck. These distinctive tumours are composed of both a mesenchymal component which is.
Jul 20, 2014 chondroid syringoma is also known as mixed tumour of the skin. Chondroid syringoma is a rare benign skin adnexal tumor, the cytological features of which have been published very rarely in the literature. It is also called as mixed tumor of skin because of the presence of. Chondroid syringoma is a rare nonmelanoma skin tumor of the head and neck, mostly benign in nature but with malignant potential. Syringoma is a tumor in the sweat ducts that are commonly harmless. Hirsch and helwig named it chondroid syringoma because of the presence of sweat gland elements in a cartilaginous stroma and the histological criteria for diagnosis. Chondroid syringoma cs of the orbit is virtually a rare benign neoplasm. Article benign chondroid syringoma applied radiology. Syringoma treatment, removal, pictures, causes, surgery. Malignant degeneration of a solitary benign enchondroma is rare, but has been reported. It presents as a firm, dermal or subcutaneous nodule, usually between 0.
Malignant chondroid syringoma mcs is a tumor of sweat glands that preferentially. This report describes the case of a chondroid syringoma occurring in the nasofacial groove of a 60yearold woman. The unusual location of chondroid syringoma made an accurate preoperative diagnosis difficult, and diagnosis was achieved only by excisional biopsy and histopathologic. First described by hirsch and helwig in 1961, chondroid syringomas css are rare, benign tumors of the skin arising from the eccrine sweat glands with tumor. Cutaneous mixed tumor chondroid syringoma basicmedical key. The pluripotentiality of the cutaneous organ is well illustrated by the many epithelial structures it can form. There are two histological types of chondroid syringoma. Chondroid syringoma is a rare skin tumor that presents as a slow growing, indolent lesion, that is more frequent in male adults and is usually benign. The incidence of cs among primary skin tumours is 0. Chondroid syringoma represents the cutaneous counterpart of mixed tumor pleomorphic adenoma of salivary glands, therefore it is also termed mixed tumour of the skin. To report a case of malignant chondroid syringoma, a rare skin tumor at joliot curie cancer institute in dakar. To the best of our knowledege, this is the second case reported in. We present here a case report of histopathologically proven malignant chondroid syringoma of scalp in occipital. Predominantly, it presents in males as an asymptomatic, slowgrowing, nontender nodule.
Apr 01, 2009 benign chondroid syringoma mixed tumor discussion a chondroid syringoma is a rare mixed tumor of sweatgland origin that has both a benign and malignant form. The patient reported in this paper presented with a painless, rapidly growing lump in the cheek. Malignant chondroid syringoma in a west african cancer institute. Malignant chondroid syringoma agrawal 1998 the journal. Chondroid syringoma is a rare skin tumor that occurs, very rarely, in the eyelids, especially the lower eyelid. Because of the unremarkable clinical presentation of this rare tumour, the diagnosis is made on microscopic examination. This article deals with dermatologic neoplasms, also known as skin tumours. Hirsch and helwig4 coined the term chondroid syringoma in 1961. Chondroid syringoma is a rare, skin appendageal tumor.
Clinically these tumors are frequently misdiagnosed. The differential diagnosis is epidermal cyst, lipoma, and. Despite its relative rarity, a benign and malignant variant have been described. The confident histological diagnosis can be obtained by immunohistochemistry study. A female presented with a subcutaneous swelling on the scalp with repeated recurrence and positive regional lymph nodes. It can be classified as eccrine and apocrine according to its pathological characteristics. Pdf chondroid syringoma is a rare appendagel skin tumor. Chondroid syringoma definition of chondroid syringoma by. An introduction to dermatopathy is found in the dermatopathology article.
The appearances were that of a dermal chondroid syringoma or benign mixed cutaneous tumour. Apr 27, 2015 giant chondroid syringoma of the breast. Unlimited viewing of the articlechapter pdf and any associated supplements and figures. A rare case of malignant chondroid syringoma of scalp. The clinical presentation of conodroid syringoma is nonspecific and its histological diagnosis can prove difficult. Billroth first described a tumor in the salivary gland with similar morphologic features in 1859. Chondroid syringoma, or cutaneous mixed tumor, is an adnexal neoplasm of either apocrine or eccrine origin. The differential diagnosis of chondroid syringoma includes basal cell carcinoma with stromal hyalinization and malignant mixed tumor of the skin. Pathology of chondroid syringoma mixed tumour of the skin.
These lesions present as nondescript dermal nodules which grow slowly. The tumour is composed of both epithelial and mesenchymal components. There was no evidence of necrosis, nuclear atypia or malignancy. Chondroid syringoma cs is a rare cutaneous tumor characterized by mixte epithelial and mesenchymal component. Apocrine mixed tumours form a well circumscribed dermal mass.
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